TAGRA 2025

The integration of microneedle technology into drug and vaccine delivery systems offers an innovative approach due to its advantages, such as applicability against a wide range of diseases, applicability in the field of immunology, minimally invasive structure, and high bioavailability. Microneedles, which are micron-sized needles designed to penetrate the outer layer of the skin and are widely used and currently in widespread use, offer a minimally invasive method for the administration of therapeutic agents, including vaccines. The microneedles proposed in our project will not only increase the bioavailability of drugs but also improve patient compliance due to their painless application and ease of use. The application of microneedle technology in vaccine development for Alzheimer's disease (AD) represents a promising frontier in immunization strategies. Micro-needles, which are small, minimally invasive devices, facilitate the direct delivery of vaccines into the skin, where they can effectively stimulate immune responses. This method has been shown to increase the immunogenicity of various vaccines, including those targeting neurodegenerative diseases such as Alzheimer's.