TURK 2025

This study aims to determine the distribution and genetic structure of ABO blood groups and Rh factor among the population of Karakol. The relevance of the study is due to the need to clarify the medical-genetic characteristics of the population, increase safety in blood transfusion practice, as well as to scientifically understand the genealogical structure of regional populations.
The research material was collected from the Issyk-Kul regional blood bank for the period 2018–2022. The data were collected from 4017 donors registered at the center. The data were grouped by gender, blood group (ABO system), and Rh factor and analyzed using statistical methods. Genetic analysis was performed based on the Hardy-Weinberg law, and the frequencies of the A (p), B (q), and O (r) alleles were calculated.
According to the results of the study, the most common blood group among the population of Karakol was O (46.6%), followed by A (32.5%) and B (17.6%), and the least common blood group was AB (3.3%). Allele frequencies were: O (r) – 0.682, A (p) – 0.233, and B (q) – 0.085. Analysis of the Rh factor showed that 86.3% of the population is Rh-positive, and 13.7% are Rh-negative. When compared with gender differences, no statistically significant difference was observed.
The scientific and practical significance of the study is the regional population In addition to clarifying biological characteristics, blood group-related to increase the safety of medical procedures, to promote blood donation optimization and further research on the genetic structure of the population The aim is to create a basis for scientific work. The data obtained will be compared with other regions of Kyrgyzstan and will also allow for the clarification of inter-population characteristics. makes.