TAGRA 2025

Pyrazoline is an important heterocyclic compound containing two adjacent nitrogen atoms and an endocyclic double bond. These derivatives possess a broad spectrum of biological activity, including antibacterial, anticancer, antitumor, anti-HIV, and anti-inflammatory activities. They generally exhibit blue fluorescence with high quantum yield in solution due to their intramolecular charge transfer properties. These strong fluorescence properties have led to their widespread use in materials science applications such as hole transfer materials, organic light-emitting diodes, dye-sensitized solar cells, electroluminescence, and optical limiters. Micelles are supramolecular structures formed by the spontaneous aggregation of surfactant molecules, particularly in aqueous environments. In a typical micelle structure, hydrophilic head groups interact with water, while hydrophobic tails are located in the interior, leading to the formation of nano-aggregates of various sizes and morphologies. These aggregates are mostly spherical, but ellipsoidal, cylindrical, or bilayer structures are also observed. In general, micelle systems are microheterogeneous two-phase colloidal systems and appear macroscopically homogeneous due to their colloidal dimensions. Aggregation occurs only under critical micelle concentration (CMC) and Kraft temperature conditions. In this process, hydrophobic interactions are considered the primary driving force, and these effects arise from the competition between hydrogen bonds of the interface and bulk water. In this study, a novel pyrazoline derivative, 4-(5-phenyl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide (TP1), was synthesized and its optical behavior was investigated in different micelle structures. For this purpose, micelles were prepared using cationic (Cetyltrimethylammonium bromide, CTAB), anionic (Sodium dodecyl sulfate, SDS), and nonionic (Tween 80, T80) surfactants at different concentrations. Absorbance and fluorescence measurements of TP1 were performed in all micelle structures prepared at room temperature.