TAGRA 2025

The synthesis of nanoparticles using plant extracts is a simple, cost-effective, and environmentally friendly method. Medicinal plants have long been valued for their therapeutic properties, and their use continues to increase today. Accordingly, extensive research is being conducted to revisit and revitalize the applications of these natural, non-chemical remedies, with modern technologies playing a major role in enhancing and optimizing their therapeutic potential. Nanoclays are among the valuable mineral materials that, due to their microstructural characteristics, high surface area, and compatibility with the body's metabolism, have become essential tools in recent studies. Curcumin, the main active component of turmeric, possesses effective therapeutic properties, particularly in boosting the immune system and combating inflammatory and infectious agents. However, its extremely low water solubility, poor bioavailability, limited gastrointestinal absorption, rapid metabolism, and fast elimination from the bloodstream pose significant challenges to its clinical use. Modifying mineral nanoclays with curcumin is one of the most effective strategies for increasing the stability, efficiency, and bioavailability of this compound, thereby enabling the development of mineral–herbal drugs with enhanced therapeutic performance. Plant-based medicines formulated with clay minerals through advanced technological methods not only offer combined therapeutic benefits but also lack harmful chemical additives and exhibit minimal side effects. Furthermore, they demonstrate high compatibility with both the environment and human metabolism. These structural features represent key standards in the pharmaceutical and medical industries.