TAGRA 2025

Colon cancer can occur as small, non-cancerous cell masses called polyps that form in the lining of the colon. Targeted cancer therapy is a method in which substances or drugs are used to target cancer cells without affecting normal cells. This method often uses nanoparticles. Among the nanoparticles that are of great importance are carbon nanotubes, which have many applications in medicine due to their unique properties such as high tensile strength and carbon structure. They are synthesized in the form of nanotubes. They are generally activated by an external agent and increase their effectiveness in dealing with cancer tissue. Infrared radiation is electromagnetic energy that is associated with atomic energy levels. If absorbed by a substance, it stimulates it. It can be used to shrink or eliminate tumors and reduce some of the side effects of cancer, such as bleeding or obstruction and to remove colon polyps or tumors that have caused obstruction of the colon or stomach. The aim of this study is to investigate the synergistic effects of infrared electromagnetic waves, carbon nanotubes, and HT29 cell line. carbon nanotubes were obtained from Merck and the dimensions of the nanoparticles were examined using a SEM microscope to ensure their size. The cytotoxicity effect and damage to the integrity of the lysosomal membrane were evaluated at time. The average diameter of the nanoparticles was in the range of less than 100 nm, and the cytotoxic effect of infrared waves and nanoparticles alone and simultaneously with infrared and nanoparticles on cancer cells showed that the simultaneous effects of nanoparticles with infrared waves were greater than the single case. This study shows that the use of nanoparticles and excitation by an infrared energy source has a great effect on dealing with cancer cells.