TAGRA 2025

Abstract
Plants of the Cousinia genus, belonging to the Asteraceae family, are traditionally used for external applications, including compresses, baths, washes, and poultices, primarily to treat eye disorders. They also serve as a source of glucofructans (inulin). Among them, Cousinia carduncelloidea Regel & Schmalh is widely recognized in Central Asian folk medicine. Despite its ethnobotanical significance, detailed studies on its chemical composition and pharmacological potential remain limited. This study presents a comprehensive evaluation of the micro- and macronutrient composition of C. carduncelloidea. A total of 50 elements were analyzed, including essential macroelements, trace metals, and potentially toxic elements, and compared with established reference ranges. Overall, the plant exhibited a balanced elemental profile, with the majority of nutrients within safe limits, supporting its traditional use. Calcium and potassium were particularly abundant, reflecting the plant’s potential nutritional value, while magnesium and sodium were slightly lower but not limiting. Trace elements were largely within normal ranges, although minor elevations in iron, arsenic, and chromium were observed. Mercury concentrations exceeded typical reference values, suggesting potential low-level anthropogenic influence, yet absolute levels remained minimal. These findings provide a baseline characterization of C. carduncelloidea, highlighting its predominantly safe elemental composition alongside minor deviations that warrant monitoring in areas subject to environmental contamination. The data contribute to understanding the plant’s nutritional and toxicological profile, supporting its continued use in traditional medicine and potential applications as a dietary supplement. This work lays the foundation for further phytochemical and pharmacological studies to explore its bioactive properties.